MACHA RESEARCH TRUST

International Centers of Excellence in Malaria Research

ICEMR

Advancing research to better understand malaria transmission, strengthen control strategies and support malaria elimination in Southern and Central Africa.

ICEMR PROJECT

Understanding Malaria to Support Control and Elimination

The International Centers of Excellence in Malaria Research (ICEMR) programme brings together multidisciplinary research to address important questions about malaria transmission and the challenges that remain in controlling and eliminating malaria.

Macha Research Trust contributes to the Southern and Central Africa ICEMR through research conducted in Zambia and in collaboration with regional and international research institutions.

PROJECT PURPOSE

Addressing the Challenges That Remain

Despite major progress in malaria control, malaria transmission continues in different settings across Southern and Central Africa.

ICEMR research seeks to understand why malaria persists despite existing interventions and to generate evidence that can help improve locally appropriate approaches to malaria control and elimination.

ICEMR

Southern & Central Africa

Research is conducted across settings with different levels of malaria transmission, allowing researchers to investigate how local epidemiology, ecology, vectors and interventions influence malaria.

RESEARCH AREAS

Multidisciplinary Malaria Research

ICEMR brings together complementary areas of research to develop a more complete understanding of malaria transmission.

01

Malaria Epidemiology

Studying the distribution, patterns and dynamics of malaria transmission to better understand where and why transmission persists.

02

Entomology

Investigating malaria mosquito abundance, distribution, infectivity, biting behaviour and resting behaviour.

03

Malaria Surveillance

Using surveillance information to understand malaria patterns and support evidence-based control and elimination activities.

04

Vector Biology

Researching mosquito vectors and their role in malaria transmission, including their behaviour and ecology.

05

Geospatial Research

Applying geographic and environmental approaches to understand the spatial and temporal patterns of malaria transmission.

06

Control & Elimination

Generating evidence that can contribute to improved malaria control strategies and long-term elimination efforts.

ICEMR STUDY COMPONENT

MUSEMO

Magnifying the Utility of Surveillance in Elimination-focused Malaria Operations

MUSEMO focuses on strengthening the use of malaria surveillance information to support elimination activities in low-transmission settings.

The study investigates approaches for identifying and responding to malaria infections and assessing implementation outcomes of focused malaria investigation strategies.

01 Measuring reductions in parasite prevalence associated with focused malaria investigation.
02 Assessing implementation outcomes of malaria investigation strategies.
ENTOMOLOGY

Understanding Malaria Mosquito Vectors

The entomology component investigates malaria mosquito vectors in the Macha area and surrounding research locations.

Research activities include studying mosquito abundance, distribution, infectivity, biting behaviour and resting behaviour. Current work also includes investigations of understudied vectors and mosquito breeding habitats.

Vector Behaviour Indoor and outdoor biting and resting patterns
Vector Ecology Distribution and breeding habitats
Vector Surveillance Monitoring mosquito populations and infection
GIS & ENVIRONMENTAL SURVEILLANCE

Mapping Malaria and Its Environment

Geographic Information Systems and Environmental Surveillance provide cross-cutting technical support for malaria research activities.

Geospatial data, environmental information and surveillance data can be combined to help researchers understand the spatial and temporal patterns of malaria.

Explore Research Infrastructure
01 Geospatial mapping
02 Environmental surveillance
03 Spatial and temporal analysis
04 Malaria surveillance data
RESEARCH SITES

Research Across Different Transmission Settings

The Southern and Central Africa ICEMR brings together research activities across different malaria transmission settings in the region.

Macha

Choma District, Southern Province, Zambia

Nchelenge

Luapula Province, Zambia

Mutasa

Eastern Zimbabwe

COLLABORATION

Research Through Regional and International Partnership

ICEMR research is supported through collaboration between Macha Research Trust and research institutions in Zambia, Zimbabwe, the United States and other countries.

These partnerships bring together expertise in epidemiology, entomology, molecular research, geospatial science, data management and public health.

Interested in Research Collaboration?

Contact Macha Research Trust to discuss research, scientific collaboration and related opportunities.

Contact MRT
RESPONSIBLE RESEARCH

Research Ethics and Participant Protection

Research involving human participants must be conducted responsibly and in accordance with applicable ethical requirements.

Macha Research Trust supports responsible research practices and appropriate ethical review and participant protection throughout its research activities.

Research Ethics & Training
SCIENTIFIC OUTPUT

ICEMR & Malaria Research Publications

Explore scientific publications arising from ICEMR and related malaria research conducted through Macha Research Trust and its collaborating institutions.

View Publications
MACHA RESEARCH TRUST

Advancing Malaria Research

Through long-term research, collaboration and scientific innovation, we continue to contribute to the evidence needed to improve malaria control and elimination.